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Exploring the synergistic potential of GLP-1R agonists with other analgesic agents could enhance therapeutic outcomes and reduce the necessity for high-dose monotherapy

By impeding glucose uptake and deactivating ATP production in mitochondria, the compounds deplete the parasite's energy reserves, leading to the paralysis of vital processes such as protein synthesis

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These agents are recommended as first-line therapy by the American Diabetes Association and the European Society of Cardiology for patients with diabetes and underlying cardiovascular disease [4, 5]

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