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Description

Methylglyoxal induces cell death through endoplasmic reticulum stress-associated ROS production and mitochondrial dysfunction

Glutaredoxin-3 from Escherichia coli

This GLP-1RA features the C-terminal extension of exendin-4, which was sequentially added to the human GLP-1 sequence that includes two substitutions (aminoisobutyric acid (Aib) at position 2 and glutamic acid (Glu) at position 16) (Extended Data Fig