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Participants were randomly assigned to receive weekly injections of retatrutide at doses of 1 mg, 4 mg, 8 mg or 12 mg, or a placebo for 48 weeks
Kumar MA, Baba SK, Sadida HQ, Marzooqi SA, Jerobin J, Altemani FH, Bhat AA
Some key findings: A large U.S
Compared with untreated individuals, those receiving GLP-1 therapy showed lower levels of pro-inflammatory cytokines (IL-6, TNF-, IL-12), higher levels of IL-10, reduced expression of endothelial adhesion molecules (ICAM-1, VCAM-1), and decreased leukocyte rolling and adhesion along the vascular endothelium [15]
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