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The Liraglutide Effect and Action in Diabetes (LEAD)-3 trial included 746 adults (age up to 79 years) with T2D randomised to liraglutide, 1.2 or 1.8 mg, or glimepiride, and found that weight loss following liraglutide did not adversely impact bone mineral density [90], although we do not have data for the impact of liraglutide at 3 mg

While this allows very elegant applications such as the generation of 3D structures in hydrogels, the SpyLock approach is much easier to implement and more economical to scale as it does not require an expression system capable of incorporating artificial amino acids