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Optimise general joint health through evidence-based lifestyle measures: Maintain a healthy weight to reduce mechanical stress on weight-bearing joints Engage in regular low-impact exercise such as swimming, cycling, or walking to maintain joint mobility and strengthen supporting muscles Apply heat or cold therapy as appropriateheat for stiffness, cold for acute inflammation Follow a balanced diet with plenty of fruits, vegetables, and whole grains

doi: 10.1016/j.diabres.2021.108737

doi: 10.1038/s41467-023-41892-5 82 DaiJHuangYJHeXZhaoMWangXLiuZSet al

doi:10.1001/jamapediatrics.2024.1576 4