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Targeting RPS6KC1 to overcome enzalutamide resistance in prostate cancer

The major enzyme superfamilies comprise cytochrome P450 monooxygenases (P450s), glutathione S-transferases (GSTs), carboxylesterases (COEs), ATP-binding cassette (ABC) transporters, and UDP-glycosyltransferases (UGTs) [5, 26, 36-39] (Figure 2)