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In clinical trials, digestive issues such as nausea, diarrhea, vomiting, and constipation were reported more frequently in people taking semaglutide than in those taking a placebo.[6] Most of these symptoms are mild to moderate and tend to improve as the body adjusts to the medication

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MAP kinase activation of CT/CGRP gene transcription is mediated through a Ras interacting site near the CRE that binds a novel and as yet unidentified zinc-fingered protein (33)

doi: 10.1111/j.1528-1167.2007.01185.x 373 ScorzaFAAridaRMNaffah-MazzacorattiMScerniDACalderazzoLCavalheiroEA