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It is hypothesized that with continued use and continued titration of insulin, superior reductions in A1C would be seen with an intensive insulin therapy compared to GLP-1 RAs

A low-fat, low-fiber diet made up of small, frequent meals with soft or blended textures works best for most people

10.1007/s13346-017-0398-z 55 EbanksJ

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Dysbiosis disrupt bile acid coupling, reducing farnesoid X receptor (FXR)/Takeda G protein-coupled receptor 5 (TGR5) signaling and impairing glucolipid metabolism