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CJC-1295, a synthetic analog of growth hormonereleasing hormone (GHRH), was developed in the early 2000s to extend the half-life and activity of natural GHRH fragments for research into growth hormone and IGF-1 pathways

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These conjugated versions enable surface-level detection of GLP-1R on live immune cells by flow cytometry, which is not possible with intracellular antibodies or antibodies directed against denatured epitopes