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Patients who experience significant nausea or appetite suppression after injection may want to time their dose to minimize impact on medication absorption

We found that GLP-1 RA use was associated with a modestly higher incidence of psoriasis and lower incidences of pemphigus and bullous pemphigoid compared with DPP-4i use, while no increased risk was observed for most other autoimmune or inflammatory skin diseases

Honda Y, Kessoku T, Sumida Y, et al

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They influence an entire cascade of hormonal pathways, and understanding these broader effects helps explain why some people struggle more than others during discontinuation