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Interestingly, liraglutides effects on the gut microbial network were weaker than metformins, resulting in a post-treatment microbiota composition that more closely resembled that of healthy controls (suggesting a normalization of dysbiosis rather than a drastic reconfiguration) (39)

The study found an inverse relation between the emptying time from the gastric pouch, and plasma GLP-1 and insulin concentration with the meal, indicating that quicker transit time led to increases in insulin and GLP-1 plasma concentration and subsequent post-prandial hypoglycemia (43)

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