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Under unfolded protein stress conditions, GRP78 binds to unfolded or misfolded proteins and subsequently activates downstream ER stress sensors, including IRE1, PERK, and ATF6, to trigger a response to unfolded proteins (Yoboue et al., 2017) , (Wei et al., 2012)

However, recent clinical trials have shown its effectiveness for weight management in individuals without diabetes, positioning it as a promising option for obesity treatment

Never shake vigorously as this can denature the peptide through mechanical stress

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(PubMed) Pilar Valdecantos M, Prieto-Hontoria PL, Pardo V, et al