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While more large-scale human trials are needed, these findings suggest that SAMe's ability to support methylation and antioxidant defense may offer profound neuroprotective benefits for patients experiencing severe, long-term cognitive dysfunction

These data showed that Herba Rhodiolae, especially when paired with GSK-3 inhibition, showcases antidepressant properties by orchestrating BDNF/TrkB-GSK-3 signaling and neuroprotective mechanisms (56)

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Erastin selectively acts on tumor cells carrying the oncogene RAS

A few companies are trying to replace APOE4 with the gene variant APOE2 , which seems to protect carriers from developing Alzheimers disease, using a combination of interfering RNA and gene therapy