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"They have to be markedly different to their natural form - which is tricky with peptides." Without a patent, he says, companies risk pouring money into a product with little financial protection

Table 2 shows patients' main baseline characteristics and outcome measures

-Synuclein has been reported to cause dysfunction of mitochondrial complex I in PD which in turn increases levels of ROS and consequently ROS-induced oxidative stress (Winklhofer and Haass 2010)

Patient Treatment Agreement and Authorization: Before proceeding, each patient signs a treatment agreement, confirming their understanding of and consent to the treatment plan