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Patients faced months-long waits, and compounding pharmacies stepped in to fill the gap

Patient evaluated in outpatient department from 2012 to 2018 Patient who age from 18 to 65 years old Exclusion Criteria Patient who had perinatal complications, shoulder surgery, or other nerve repair procedures of the brachial plexus Allergy or intolerance to constraint intervention materials Clinical cases Demonstrative case: A 50-year-old man (Patient 1 of Table 1) presented to a community-based outpatient clinic with left arm weakness and numbness following a traffic accident 2 months before presentation, which involved traumatic subdural hemorrhage, facial bone fracture, left second rib fracture, and pneumothorax

This response is regulated by evolutionary conserved signaling pathways that promote transcriptional changes, which in turn limit tissue damage and foster repair and stress resistance (1)

1113 Made in China Manufactured for: Dynarex Corporation Orangeburg, NY 10962 www.dynarex.com Revised: 11/2019 PRINCIPAL DISPLAY PANEL: B-12 Compliance Injection Kit NDC 49836-527-01 RX-Only B-12 Compliance Injection Kit Kit Contains: 1 Cyanocobalamin Injection, USP 1,000 mcg/mL (1 mL) 1 Sterile Isopropyl Alcohol 70% Prep Pad 1 Pair Nitrile Powder Free sterile Gloves (Size 7.5) 1 Sterile Towel Drape 1 Sterile Adhesive Bandage 1 Dose Needles and Syringes Not Included B-12 Compliance Injection Kit DISTRIBUTED BY: SCHMIGS HAUPPAUGE, NY 11788 NDC 49836-527-01 MANUFACTURED BY: Rx Pharma Pack HAUPPAUGE, NY 11788 Questions/Comments 1-844-632-7898 Kit Contents: Cyanocobalamin Injection, USP 1,000 mcg/mL* (Manufactured by American Regent) Each mL contains: benzyl alcohol 1.5%

doi: 10.1038/s41598-022-08771-3