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The studys authors emphasized that their work is observational and cannot definitively rule out confounding factors

Drug accumulation with improper spacing If injections are spaced too close together, tirzepatide concentration can build to levels higher than intended

While peptides are generally less immunogenic than larger proteins, they can still trigger antibody formation in some patients

Specifically, the exception does not apply broadly to a general population

Hence, whilst cysteine is one of the less common amino acids, it is often highly conserved within protein functional groups (Marino and Gladyshev, 2010)