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The overexpression of PGC-1 adeno-associated virus in the brain region of APP23 model mice was observed to result in increased transcription of growth factors, reduced levels of BACE1, and diminished A-mediated neuroinflammation, which collectively led to reduced -amyloid production and neuronal loss (Katsouri et al., 2016)

Bridge, Oral administration of -glutamylcysteine increases intracellular glutathione levels above homeostasis in a randomized human trial pilot study

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A committee recommendation, placement on a statutory list, FDA approval, and a laboratory suppliers research-use-only position are separate matters

10.1038/nrg.2016.150 Nat