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These include: resistance training to stimulate muscle protein synthesis adequate protein intake to support tissue repair sleep optimization to regulate cortisol and metabolic hormones stress reduction to prevent chronic catabolic signaling These foundational habits help ensure that weight loss occurs in a way that supports overall metabolic resilience rather than undermining it

Ipamorelin dosing (typically 200 to 300 mcg subcutaneously, once or twice daily, cycled 5 days on / 2 days off or similar protocols) should follow the prescriber's clinical judgment and the patient's GH-axis response

Rhee SG

Am J Gastroenterol 2024;119(10S):S586S587.Article 25

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