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Retatrutide should not significantly impact sleep quality for most users, though some report improved sleep as excess weight decreases and sleep apnea symptoms improve

Patients should be strongly cautioned against purchasing retatrutide from unregulated online pharmacies or overseas suppliers

GLP-1 supplements are over-the-counter products marketed as natural alternatives to prescription GLP-1 receptor agonists, such as Wegovy and Ozempic

Simultaneously, these drugs suppress glucagon secretion, which prevents the liver from releasing excess glucose into the bloodstream

This is the largest mean percentage weight loss reported in any randomized controlled trial of an anti-obesity pharmacotherapy to date