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It should be noted that the rate of WL with the novel pharmacotherapies could be individualised, something that is not feasible with bariatric surgery, however the optimal WL rate to optimise the risks for nutritional complications and/or cholelithiasis will need further research [107]

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This also produces transient lower esophageal sphincter relaxation, which facilitates GERD (55)

CJC-1295 with DAC requires additional care to avoid thiol-reactive reagents and alkaline conditions