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Nature Reviews Neurology 15:429430

Shifts may begin within 37 days of increased fiber and polyphenols, with full metabolic benefits in 36 weeks

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The reuptake of GABA is mediated by GATs, with GAT-1 utilizing the electrochemical gradients of Na+ and Cl - to transport extracellular GABA back into presynaptic and postsynaptic neurons, thereby facilitating the termination of GABAergic signaling

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