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Stomach irritation: Antibiotics can be harsh on the stomach lining, and if the pill sits there longer due to slow gastric emptying, you might feel more localized irritation or nausea

Common side effects of semaglutide include: Nausea Vomiting Diarrhea Constipation Abdominal pain Indigestion (dyspepsia) Abdominal distension Decrease in appetite Belching (eructation) Gas (flatulence) Gastritis Gastroenteritis Viral gastroenteritis Gastroesophageal reflux disease (GERD) Gallstones (cholelithiasis) Headache Fatigue Dizziness Low blood glucose level (hypoglycemia) Severe hypoglycemia Diabetic retinopathy Bleeding in the vitreous, the gel-like substance within the eye (vitreous hemorrhage) Blindness Hair loss (alopecia) Antibody development Low blood pressure (hypotension) Drop in blood pressure when getting up from sitting or lying down (orthostatic hypotension) Less common side effects of semaglutide include: Discomfort and redness at the site of injection Inflammation of the pancreas (pancreatitis) Increase in amylase, the enzyme that helps digest carbohydrates Increase in serum lipase, the enzyme that breaks down fats Hemorrhoids Biliary tract disease Gallbladder disease Inflammation of the gallbladder (cholecystitis) Need for removal of gallbladder (cholecystectomy) Acute kidney injury Increased heart rate Skin rash Hives (urticaria) Bullous pemphigoid, a rare skin disorder with fluid-filled blisters Severe allergic reaction (anaphylaxis) Call your doctor immediately if you experience any of the following symptoms or serious side effects while using this drug: Serious heart symptoms include fast or pounding heartbeats, fluttering in your chest, shortness of breath, and sudden dizziness

If you experience persistent poor intake, ongoing nausea/vomiting, or signs of dehydration while taking GLP-1 medications, contact your healthcare team promptly

More information can be found in the Summary of Product Characteristics and Patient Information leaflets which will be published on the MHRA Products website within 7 days of approval

[81] Society and culture [edit] Legal status [edit] In December 2016, a new drug application was filed with the US Food and Drug Administration (FDA), and in October 2017, an FDA advisory committee approved it unanimously