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This natural form of B12 appears safe and may improve nerve pain (diabetic neuropathy) and heart health at doses of 500 mcg three times a day or 1,500 mcg daily

(For a full overview of vitamin B12 benefits beyond mood, start with our master guide.) When the brain doesn't have the raw materials it needs to produce neurotransmitters and maintain healthy nerve function, mood is one of the first things to shift

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