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Nerve damage involves inflammation, vascular compromise, neurotrophic factor deficiency, oxidative stress, and mitochondrial dysfunction

Generally, BPC 157 rats had a markedly attenuated course completely preventing convulsions as well leading to full reversal when applied in rats exhibiting generalized convulsions

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More specifically, they noted that at least one subject's Central corneal endothelial cells (CEC) density measurement was not completed before enrollment, which was one of the enrollment criteria, and another enrolled subject had Intraocular pressure (IOP) that was outside the criteria