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Finally, long-term tirzepatide treatment significantly raised BAT levels of several TCA cycle intermediates, including fumarate, malate, and -ketoglutarate

Furthermore, GLP-1 has beneficial cardiovascular effects in humans by lowering blood pressure and improving myocardial function [20, 21], although in rats this peptide significantly increases arterial blood pressure and heart rate [22, 23]

It's also important to obtain adequate nutrients that support bone density, especially if you're eating less while taking GLP-1s

Tirzepatide is administered as a once-weekly injection of tirzepatide delivered via the KwikPen device

[DOI] [PubMed] [Google Scholar] Martin V., Hoekman J., Aurora S.K., Shrewsbury S.B