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In line with our observations, BSO co-administration in the final week of a 7-wk ethanol feeding regime in mice, which caused a 72% decline in hepatic GSH, was shown previously to exert a hepatoprotective effect 15

In MS, elevated P2X 7 receptor activation promotes cytokine release and oligodendrocyte injury, contributing to demyelination and neurodegeneration

The core reactions of glutathione synthesis are conserved across various organisms, but plants have diversified both the regulatory mechanisms that control its synthesis and the range of products derived from this pathway