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Nrf2 plays a crucial role in protecting cells from oxidative damage, inflammation, and toxins by activating the expression of protective genes

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Discussion This review evaluates the effect on HR of six approved GLP-1 RAs, categorized into a short-acting sub-class with half-lives of 35 h (exenatide BID and lixisenatide) and a long-acting sub-class with half-lives ranging from 12 h to several days (liraglutide, exenatide LAR, albiglutide and dulaglutide) [16]

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