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Local GI Effects: For applications related to gut lining, oral administration may provide direct topical contact with intestinal tissues in theory
BPC-157 has been reported to upregulate VEGFR2 (vascular endothelial growth factor receptor 2) and activate the Akt-eNOS pathway, which raises nitric oxide production in blood-vessel walls (Hsieh et al., Journal of Molecular Medicine, 2017
Essentially, the clinic administering the peptide (which the patients paid for out-of-pocket) later phoned patients to ask if they felt better, and wrote up the responses
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