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doi: 10.1007/s00204-016-1757-0 159 HamblinM

Inflammatory cytokines including tumor necrosis factor alpha (TNF), interferon gamma (IFN), and interleukin-1 beta (IL-1), cause beta-cell dysfunction by impairing ATP production, inducing DNA damage, and promoting apoptosis ( Figure 3 ) (84, 85)

Conclusions TZP marks a revolution in WL and insulin treatments for overweight and obese patients, far surpassing the clinical efficacy of conventional interventions

Glutathione (GSH), the main intracellular antioxidant, increases upon amino acid (AA) administration in preterm infants, without an accompanying rise of the fractional synthesis rate of GSH (FSR GSH ) This study investigated the mechanism behind this increased GSH concentration by determining GSH synthesis in the first days after birth using stable isotope techniques in very low-birth-weight (VLBW) infants receiving i.v

Deletion of RAMP1 signaling enhances diet-induced obesity and fat absorption via intestinal lacteals in mice