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In men, lower GPx4 activity shows up in those with poorer sperm quality, and it correlates most strongly with forward motility

Jamalpoor A, van Gelder CA, Yousef Yengej FA, Zaal EA, Berlingerio SP, Veys KR, Pou Casellas C, Voskuil K, Essa K, Ammerlaan CM, Rega LR, van der Welle RE, Lilien MR, Rookmaaker MB, Clevers H, Klumperman J, Levtchenko E, Berkers CR, Verhaar MC, Altelaar M, Masereeuw R, Janssen MJ (2021) Cysteamine-bicalutamide combination therapy corrects proximal tubule phenotype in cystinosis