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This may include gradually increasing your dosage (titration) to help you adjust to treatment

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The principal incretins are the glucose-dependent insulinotropic polypeptide (GIP) and the glucagon-like peptide-1 (GLP-1), representing the endogenous physiological substrates for DPP4 activity [34, 35]

However, many individuals struggle with adherence to CPAP therapy, and lifestyle changes like weight loss can be difficult to achieve

"If a patient is on semaglutide and at maximal dose, then changing to tirzepatide may help since that medication affects two hormone receptor types, as opposed to one." Dr