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Metformin and GLP-1 receptor agonists are two separate medication classes that address metabolic health in fundamentally different ways

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Most participants (63.8%) were women

(See What to Consider When Buying) L-citrulline safety and side effects: L-citrulline supplementation appears to be generally safe and well tolerated in healthy individuals, although occasionally, gastrointestinal upset and heartburn have been reported, and it should be used with caution by people on medication that lowers blood pressure