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This may be because cardiac regeneration therapies directly restore damaged myocardium, whereas remodeling-focused interventions primarily modulate upstream pathological drivers (e.g., inflammatory cascades or metabolic dysregulation) that operate through complex, interconnected signaling networks to induce structural changes

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doi: 10.1016/j.tibs.2013.12.001 92 LamarkTJohansenT

In youth, weight reduction improved interoceptive accuracy and reduced body dissatisfactionassessed across multiple bodyrepresentation domainsunderscoring that body image is multicomponent and does not necessarily change in lockstep with weight [74]

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