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Myburgh, "Three Weeks of Creatine Monohydrate Supplementation Affects Dihydrotestosterone to Testosterone Ratio in College-Aged Rugby Players," Clin

Key findings published in JAMA Internal Medicine: Statistically significant and clinically meaningful improvements in satisfying sexual events Approximately 0.5-1.0 additional satisfying sexual events per month compared to placebo Significant improvements in desire scores on the Female Sexual Function Index Significant reduction in distress associated with low sexual desire Effects maintained throughout 24 weeks without tolerance development Male Erectile Dysfunction Research Research in male erectile dysfunction has shown promising results, particularly in men with psychogenic ED or those who fail to respond to PDE5 inhibitors

Stratified by lifestyle intervention Continuation of lifestyle interventions after treatment discontinuation may affect the extent of weight regain

While many anecdotal success stories suggest it can be a valuable tool in a regenerative medicine toolbox, it is still under ongoing investigation