GLP-1s have dominated the peptide game and the cultural conversation for the past few years, but Jeffrey Lee, MD, a board-certified plastic surgeon in Boston, notes that there are many others emerging, and they may have a wide range of effects
Patients may struggle to lift the front part of the foot, leading to toe dragging and difficulty walking
Key findings include: Weight regain averaged 0.8 kg (1.8 lbs) per month after stopping injections Most participants returned to their starting weight within 18 months Regain was 0.3 kg per month faster than traditional dieting and exercise, regardless of initial weight loss The research highlights the importance of ongoing clinical oversight and behavioural support, as 9 in 10 UK users currently buy these drugs privately, often without NHS guidance
Use a new, sterile needle and syringe for every draw
Understanding the mechanisms behind this side effect and implementing appropriate management strategies enables patients to continue benefiting from tirzepatide therapy whilst maintaining quality of life