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In addition to their potent metabolic actions that reduce hyperglycaemia and body weight, GLP-1RAs also lower the risk of major kidney, cardiovascular and mortality outcomes across broad populations with cardiovascular disease or CKD, with and without diabetes or obesity

This activation prompts intestinal endocrine cells to activate the BA-TGR5-GLP-1 axis, leading to increased GLP-1 release, which in turn facilitates muscle glucose absorption [87, 97, 105]

Mounjaro pens deliver a fixed dose in a fixed volume (0.5 mL per injection)

Obesity and diabetes are the greatest contributors to preventable chronic illness nationally and in Rhode Island

Lancet 2009