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When exercise was added, these negative effects were largely prevented: exercised rats had higher total bone mineral content, lean mass, and serum IGF-1, and their bone mechanical strength was maintained despite reduced energy availability

55 Likewise, data on mean BMI among HFrEF participants may not reflect the presence and severity of obesity as a target for the potential effectiveness of GLP-1 RAs

10.1111/j.1467-7652.2011.00611.x 70 LeonardisS.DipierroN.DipierroS