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In the postmenopausal state, reduced sex hormonebinding globulin increases androgen bioavailability and promotes insulin resistance [136]

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Anecdotally, people with food addiction who find GLP-1s helpful in this regard talk about how the medication turns down the volume of food noise in the brain, by which they mean the constant thoughts and cravings for certain types of food, Anna Lembke, MD, professor of psychiatry and behavioral sciences at Stanford Medicine These patient reports prompted researchers to take a closer look at what was happening in the brain