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Zhu et al., 2018)

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First, we leveraged a large, geographically diverse real-world database spanning multiple US health systems, enabling the evaluation of treatment effectiveness in a clinically relevant population of adults treated specifically for obesity managementrather than glycaemic control

In summary, while GF mice still show a trend toward higher locomotor activity than SPF mice, the difference is not as pronounced as reported in previous studies 14,15,60,61

Now, they are reshaping the landscape of obesity treatment and metabolic health with impacts that go far beyond the scale