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J Exerc Physiol Online 2000;3:2636

[30] A 2000 study to determine increases of eumelanin expression in seven, "normal volunteers" administered [Nle 4 , D-Phe 7 ]-MSH concluded that, "the tanning induced by Melanotan in the face and forearm is associated with a significant increase in the eumelanin content of the human skin." [31] Three 2004 Phase I clinical trials sought to establish the safety of [Nle 4 , D-Phe 7 ]-MSH therapy combined with UV-B light or sunlight exposure

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Secondstrand synthesis, end repair, adaptor ligation, and PCR amplification were performed to generate the final sequencing libraries

Some are research-grade peptides used in clinical settings, while others are low-dose, supplement-style capsules with little proven efficacy