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Importantly, older adults ( 65 years) experienced similar changes without evidence of excessive lean mass loss [67]

doi: 10.1016/j.lfs.2020.117996 4 ScheltensPDe StrooperBKivipeltoMHolstegeHChtelatGTeunissenCEet al

The issue isnt safety

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These findings suggest that once AD pathology is established and cognitive symptoms emerge, the neurodegenerative cascade may be too advanced or may have become independent of the metabolic and inflammatory pathways that semaglutide effectively targets