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N Engl J Med (2010) 363(12):11856

Buyer takeaway: GLP-1 medications including compounded and brand-name FDA-approved versions carry documented side effect and serious-risk profiles, including gastrointestinal effects, pancreatitis risk, thyroid C-cell tumor risk (Boxed Warning on FDA-approved products), and contraindications including personal or family history of medullary thyroid carcinoma, MEN 2, and active eating disorders

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If you do not feel the urge to drink water because of the medications effects on your brains reward centers, you may become dehydrated without realizing it

N., & Rolfes, S