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It is also contraindicated in patients with a personal or family history of medullary thyroid carcinoma (MTC) or in patients with multiple endocrine neoplasia syndrome type 2 (MEN 2)

Losing weight can feel like an uphill battle

Managing type 2 diabetes and obesity has seen significant advancements with the introduction of GLP-1 receptor agonists like semaglutide and the newer dual agonist [...] Read More Join 50,000+ readers using Doctronic to understand symptoms, medications, and next steps

It is studied as a selective inhibitor of nicotinamide N-methyltransferase (NNMT), an enzyme linked to metabolic and oncogenic pathways in research models

Lee JK, Koppelmans V, Riascos RF, Hasan KM, Pasternak O, Mulavara AP, et al