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Description

AJP: Renal Physiology

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Recently, accumulating evidence suggests that gut microbiome dysbiosis may affect the development and progression of NIU through potential mechanisms, including translocation, molecular mimicry, and bystander activation

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however, this has not been confirmed in humans, and this is not a formal contraindication in UK or EU prescribing information for approved GLP-1 receptor agonists

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The risk is dose-dependent: at 300 mg/day, incidence drops to roughly 0.1%

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As uterine fibroids grow larger, they cause menstrual bleeding to increase

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