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Start by adding more fiber-rich foods like fruits, vegetables, whole grains, and legumes to your meals
People who took GLP-1 drugs had lower risk of all kinds of drug and alcohol addiction A large epidemiological study of more than 600,000 veterans with diabetes suggests GLP-1 weight-loss medications may reduce drug- and alcohol-related overdoses and deaths PharmaceuticalsFebruary 26, 2026 Head-to-head trial pitting Eli Lillys oral GLP-1 against oral semaglutide underscores efficacy of weight-loss pills A new trial found that Eli Lillys GLP-1 pill resulted in greater reductions in blood sugar levels and weight than oral semaglutide did, but fewer people stayed on it Lauren J
Another consideration is electrolyte disturbance
2024, Diabetes Obes Metab 26(3):911-923, which confirmed similar weight loss magnitudes)
The tirzepatide dose can then be increased every 4 weeks based on efficacy and tolerability
