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The British Menopause Society has highlighted this concern, noting that while there is currently no robust data showing that GLP-1 receptor agonists definitively affect oral progestogen dosing requirements, bleeding patterns, or endometrial risk, the theoretical concern is valid and warrants monitoring

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Continue weekly weigh-ins and monthly metabolic marker checks for at least six months

Body weight affects dosing

Kinetics of PfGrx mutants confirm a conserved mechanism In a third set of experiments, we tested whether our findings for ScGrx7 catalysis can be generalized