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(Its notable that, in general, inflammation is more likely to fall during GLP-1 treatment.) But to be safe, its worth watching your white blood cells

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Animal models of colitis have demonstrated that GLP-1 receptor activation may reduce intestinal inflammation through multiple mechanisms, including modulation of pro-inflammatory cytokines such as tumor necrosis factor-alpha (TNF-) and interleukin-6 (IL-6), enhancement of intestinal barrier function, and reduction of oxidative stress