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Simultaneously, released Cu 2+ causes redox reaction with the intracellular overexpressed GSH, and subsequently produces Cu + for initiation of Fenton-like reactions, resulting in the production of OH and robust anticancer therapy

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(A, B) Clusters of differentially accessible regions identified in Figure 1A were queried for (A) H3K27ac and (B) H3K4me1 ChIP-seq signal in human monocytes after 0h, 1h, 4h, and 24h of BDG exposure

The antioxidant properties of glutathione help eliminate the dullness caused by accumulated cellular damage