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Abstract The lysyl oxidase family of enzymes (LOXs) catalyze oxidative deamination of lysine side chains on collagen and elastin to initialize cross-linking that is essential for the formation of the extracellular matrix (ECM)

The increased bone formation was attributed to larger bone dimensions and increased cortical cross-sectional area, as determined by in vitro measurements with peripheral quantitative computed tomography (pQCT) and Archimedes' principle

This means the 10 to 200 mcg/kg doses that dominate the animal literature translate to a rough human equivalent of approximately 1.6 to 32 mcg/kg, or about 120 to 2,400 micrograms for a 75-kilogram adult

Rarely do some patients experience reduced sexual desire or erectile function, warranting individualized clinical decisions

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