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By phosphorylating Bad and CREB, activated ribosomal protein S6 kinase beta (RSKs) can inhibit apoptosis [56, 57]

doi: 10.3389/fpls.2025.1718992 Received 05 October 2025 Accepted 27 October 2025 Published 13 November 2025 Volume 16 - 2025 Edited by Qunfeng Zhang, Chinese Academy of Agricultural Sciences (CAAS), China Reviewed by Yunqiu Yang, Anhui Agricultural University, China Yuanzhi Shi, Chinese Academy of Agricultural Sciences, China Xiangxiang Huang, Fujian Agriculture and Forestry University, China Updates Copyright 2025 An, Mao, Huang, Leng and Chen

Importantly, because of their atypical clinical features, amelanotic melanomas may have a delay in their diagnosis and, consequently, are often more advanced than pigmented melanomas when diagnosed

In fact, in cells undergoing lethal oxidative stress, cellular protein-SSG levels show a positive relationship with GSSG levels 39